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It happens many times those examiners set questions which the boys are not expected to know as they are not included in the syllabus. I shall be very careful n framing questions. An examiners job is to test the comprehension of the boys. This does not demand the questions set in the paper are more difficult than the text itself. Sometimes even well prepared students fail to do justice into the examination hall because questions are not in level with the expected attainment of the boys. I shall therefore try to understand the limitations the boys and set questions accordingly. A boy who understands the text soul gets a pass. That way I sell try to be judicious. Marking answer books again is a job which requires greater skill and experience on the part of an examiner. I shall make a careful examination of the answers. Sometimes the answers are not what we expect.



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This balance between added assurance of sterility afforded by a validated sterile claim and the substantial added cost to attain that added assurance is one that must be made by biopharmaceutical manufacturers. The choice must be made case by case and is most likely to be driven by a risk assessment of each unit operation as well as by the manufacturing process as a whole. In upstream processing, bacterial e. g. , Escherichia coli cell cultures tend to be operated in short time frames and are fairly resistant to overgrowth by low levels of contaminant bacteria. In such cases, a user may consider that single use disposable bioreactors and culture media or other nutrient additives prepared in single use systems may be safely operated under microbial control provided by irradiation without sterilization validation. Mammalian cell cultures, by contrast, are often run for extended periods of time e. g. , up to two weeks and are generally more sensitive to bacterial contamination. In such cases, the additional assurance provided by sterilization validation may be merited, although the high but unspecified probability of nonsterility afforded by gamma irradiation for microbial control may be adequate during process development and even production. Cell harvesting and downstream processing steps centrifugation, depth or membrane filtration, and chromatography, with intermediate holding are rarely validated for sterility due to complexities and/or limitations of their equipment, especially during process development.



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In addition to performing autopsies, identifying missing persons, dealing with natural disasters, terrorism and helping criminal justice through science, Sampson makes it clear what her office is all about:We feel we have a big mission in education, she said. This is the first time weve had the students in. We speak at schools and see so much interest from young people. During the tour, which coincided with National Forensic Science Week,students heard from Sampson; Dr. Jennifer Hammers, deputy chief medical examiner for Brooklyn and Staten Island; and Dr. Bradley Adams, city director of forensic anthropology. Adams showed how forensic science played a role in local investigations, including solving the2005 mob hit at the historicKreischer Mansion homicide in Staten Island. In the labs, students saw every step of DNA analysis, from determining whether a piece of evidence has enough DNA for testing to generating DNA profiles of criminals and missing persons. Megan Erhardt, a 16 year old junior fromHuntington, Long Island, is aiming for a career as a forensic biologist and hoping to eventually work for the FBI. Erhardt, who has always had a passion for science, skipped teaching summer camp to attend. She, like others, admitted that television played a role in piquing her interest in forensics.



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It hasnt been smooth, he says, citing problems such as internet access, scheduling classes, teachers unfamiliar with online tuition, and subjects such as physical education being awkward to teach remotely. In China teachers have to submit lesson plans for review by censors, which has led to delays. Students have been spamming the main online teaching app with one star reviews in an effort to get it removed from the app store. And Xue Hua, a mother of two in Jiangxi province, has been printing out all the learning materials for her 16 year old son, Guo Guo, because she worries about too much screen time. Even done properly, online learning is a poor substitute for the kind that happens in a classroom. On average, students fare worse working online, especially those with less strong academic backgrounds, says Susanna Loeb of Brown University. Online courses can be an asset when students cannot be in school, but she reckons that they are suboptimal for most and argues that long periods of time spent away from actual schools will probably lead to childrens education suffering. Online learning has clear potential. Educational technology powered by artificial intelligence can help children in poor countries with iffy schoolssupposing they have internet access. In 2018 researchers found that after four and a half months of using an Indian app called Mindspark, which tests basic language and maths skills, children made more progress in these areas than those in the control group. But the success of such initiatives relies on preparation and organisation, not sudden scrambles to teach existing curriculums to entire populations of students in the midst of a pandemic.

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